Startups & Entrepreneurs
From first spark to full-scale success, the Ozarks Region is where entrepreneurs find the support, resources, and connections they need to thrive. With a culture of collaboration, low barriers to entry, and a network of mentors and investors, the region is a launchpad for bold ideas.
Why This Industry Thrives Here
Cost-Efficient Operation
Lower operating and living costs stretch early-stage capital further.
Talent Pipeline
Universities, technical schools, and training programs supply graduates in business, engineering, health care, and IT to fuel new ventures.
Collaborative Culture
A connected business community makes it easy for founders to access mentors, advisors, and peers.
Room to Scale
From co-working spaces to build-ready sites, entrepreneurs can start lean and grow seamlessly.
Local Leaders
Jack Henry & Associates
Financial technology solutions provider and regional headquarters.
Bass Pro Shops
Outdoor recreation retailer and global headquarters.
O’Reilly Automotive
Automotive aftermarket retailer with corporate headquarters.
Digital Monitoring Products (DMP)
Founded in Springfield, now an international security technology manufacturer.
JMARK
A managed IT services provider that has scaled into one of the region’s most recognized technology firms.
Key Startups & Entrepreneurs Facts
The eFactory has supported 200+ startups since founding.
Regional startups have raised over $100 million in venture funding.
5+ active angel groups invest in regional startups.
Support & Resources
Entrepreneurs receive support through:
- The eFactory An innovation hub offering accelerator programs, coworking, mentorship, and corporate innovation partnerships.
- Jordan Valley Innovation Center Partnerships with private industry in advanced R&D, specializing in materials science, biotech, and electronics.
- Local Chambers & Development Groups Provide networking, advocacy, and small-business support.
- Universities & Colleges Missouri State, Drury, Evangel, OTC, and Southwest Baptist University all offer business, innovation, or entrepreneurship programming.
- Show-Me Network Connects entrepreneurs to resources and opportunities.

Ready to Build Your Company in the Ozarks?
The best insights come from conversations. Reach out and our team can provide tailored guidance, strategic connections, and on-the-ground knowledge to turn business possibilities into actionable plans.