Ozarks Region

Greene County

As the economic engine of the Ozarks Region, Greene County is home to Springfield—the state’s third-largest city—and a dynamic mix of industries, innovation hubs, and cultural attractions. Communities like Republic and Willard contribute to the county’s growth, offering a blend of business opportunity, livability, and strategic access to national markets.

Greene County Snapshots

Jordan Valley Park, looking toward Hammons Tower in Springfield, Missouri

Springfield

The county seat and largest city, serving as the commercial, healthcare, education, and cultural center of southwest Missouri.

Sunny sidewalk in a suburban neighborhood

Republic

One of Missouri’s fastest-growing cities, known for industrial development, retail expansion, and strong residential growth.

Father helping son learn how to ride a bike

Willard

A family-oriented community with a growing housing market and easy access to Springfield’s employment base.

Exterior of Bass Pro Shops entrance with customers entering and exiting
Several semi-trucks backed up to doors at a distribution facility

Major Employers

  • Bass Pro Shops

    National outdoor retail leader headquartered in Springfield.

  • O’Reilly Automotive

    Fortune 500 auto parts retailer headquartered in Springfield.

  • CoxHealth

    Regional healthcare system serving southwest Missouri.

  • Mercy Springfield Communities

    Multi-state healthcare network with hospitals and clinics.

  • SRC Holdings Corporation

    Employee-owned manufacturing and remanufacturing company headquartered in Springfield.

  • Jack Henry & Associates

    National financial technology company with a significant operational presence in the region.

  • Prime Inc.

    Major freight, temperature-controlled, flatbed, tanker, and intermodal trucking company with its national headquarters in Springfield.

Economic & Community Highlights

Industry Strengths

Advanced manufacturing, healthcare, technology and innovation, distribution and logistics.

Workforce Highlights

Deep labor market supported by Missouri State University, Drury University, Evangel University, and Ozarks Tech.

Infrastructure

Located at the crossroads of U.S. 65, U.S. 60, I-44, and multiple rail lines, with Springfield-Branson National Airport offering direct air service to major hubs.

Quality of Life

Urban amenities, diverse cultural offerings, extensive parks and trails, and affordable cost of living.

Resources & Data

Demographics Data
Available Sites
Workforce Statistics
Community Profile
Springfield MSA Demographic Profile
Professional man and woman walking and talking, looking at a digital tablet she has in one hand

Your Next Move Starts Here

From global headquarters to emerging startups, Greene County delivers the talent, infrastructure, and community that make business thrive.